Millwall have added loan signings Jason Puncheon and Calvin Andrew to their squad for the trip north.
Scott Barron is suspended, while Chris Hackett is out with a hip injury and forwards Kevin Lisbie and Theo Robinson are both sidelined with knee problems.
MATCH PREVIEW
Middlesbrough boss Tony Mowbray turns 47 on Monday but may not feel like celebrating, as his team could be in the bottom three by then.
Boro, who have won two matches and lost two since Mowbray took over, are above the relegation zone only on goal difference and will drop into it if they fail to win and either Bristol City or Crystal Palace pick up three points.
But history is certainly on their side ahead of the visit of Millwall, who have lost on their last five visits to Teesside and have not won there for 43 years.
The Lions have also been struggling for form. They are without a win in four matches, but tend to start away matches strongly. Millwall have opened the scoring in six away games this season - more than any other team in the Championship.
MATCH FACTS
Head-to-head
• Middlesbrough are unbeaten in 13 home league matches against Millwall (W11, D2), and have scored a total of seven goals in their last two matches against them.
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• Millwall's last away win against Boro was a 1-0 victory in the old Second Division in September 1967.
Middlesbrough
• Boro have won only two of their last 10 matches.
• They are averaging a point and a goal per game, having scored 17 goals and collected 17 points from their 17 matches this season.
• The Teessiders have scored in all their home matches this term - a feat matched only by Coventry.
• Of their 17 league goals, 13 have been scored at home.
• David Wheater is in line for his 150th appearance for the club.
Millwall
• Millwall have won only one of their last six games.
• They have won all four Championship games in which they have scored more than one goal, and lost all five in which they have conceded more than one.
Source: BBC Sport
Source: BBC Sport